Facilitation of electric forepaw stimulation-induced somatosensory activation in rats by additional acoustic stimulation: An fMRI investigation

BOLD fMRI of forepaw stimulation at different amplitudes in mice

Electric acoustic stimulation in children.

BACKGROUND/AIMS The combined electric acoustic stimulation (EAS) of one ear is a topic that has received considerable attention over the last 10 years, the technique having originally been introduced by Prof. Christoph A. von Ilberg for so-called borderline adult cochlear implant (CI) candidates. Its development has followed several parallel strands, including the modification of existing surgi...

Imaging oxygen consumption in forepaw somatosensory stimulation in rats under isoflurane anesthesia.

The cerebral metabolic rate of oxygen (CMRO2) was dynamically evaluated on a pixel-by-pixel basis in isoflurane-anesthetized and spontaneously breathing rats following graded electrical somatosensory forepaw stimulations (4, 6, and 8 mA). In contrast to alpha-chloralose, which is the most widely used anesthetic in forepaw-stimulation fMRI studies of rats under mechanical ventilation, isoflurane...

Investigation of the early response to rat forepaw stimulation.

The role of relative cerebral blood volume (rCBV) in the early response of blood oxygenation level-dependent (BOLD) signal following sensory stimulation was assessed. Magnetic resonance imaging (MRI) measurements of rCBV and BOLD signal as a function of time (t) were compared with relative cerebral blood flow (rCBF) obtained by laser doppler flowmetry during a repeated epoch of rat forepaw stim...

Physiological Mechanisms in Combined Electric-Acoustic Stimulation.

OBJECTIVE Electrical stimulation is normally performed on ears that have no hearing function, i.e., lack functional hair cells. The properties of electrically-evoked responses in these cochleae were investigated in several previous studies. Recent clinical developments have introduced cochlear implantation (CI) in residually-hearing ears to improve speech understanding in noise. The present stu...